Zynext Ventures USA LLC, the venture capital arm of Zydus Lifesciences, has announced an investment in Illexcor Therapeutics, a biopharmaceutical company pioneering next-generation oral therapies for sickle cell disease (SCD). This strategic investment highlights Zynext Ventures’ focus on supporting healthcare innovations that address critical unmet medical needs.
Illexcor is developing a first-in-class oral drug designed to target the underlying cause of SCD. The lead candidate, ILX002, currently in preclinical development, binds to Hemoglobin S to prevent polymerisation and sickling—mechanisms responsible for the disease’s debilitating effects. If successful, this therapy has the potential to modify the disease course and improve the quality of life for patients.
Commenting on the development, Dr Sharvil Patel, Managing Director of Zydus Lifesciences, said, “This investment reflects our commitment to patients battling rare and orphan diseases. Recognizing the profound impact of sickle cell disease on patients’ lives, we are pleased to support Illexcor in their efforts to develop a novel therapeutic solution addressing this critical unmet medical need.”
Jay Kothari, Director of Zynext Ventures, said, “This investment is consistent with Zynext Ventures’ objective of identifying and fostering transformative early-stage healthcare innovations. Beyond the financial backing, Zynext Ventures will leverage its unique data analytics and strategic expertise to accelerate Illexcor’s path to delivering this potentially life-changing therapy globally.”
Andrew Fleischman, CEO of Illexcor Therapeutics, expressed optimism about the partnership, noting that the investment will support the transition of ILX002 into clinical trials later this year. He underscored the drug’s potential impact not only for SCD patients in the United States but also for millions worldwide.
Sickle cell disease affects up to 10 million people globally, significantly impairing life expectancy and quality of life. Despite advancements in treatment, the need for highly effective, disease-modifying oral therapies remains urgent. The collaboration between Zynext Ventures and Illexcor could play a pivotal role in addressing this need.
Zynext Ventures, the investment arm of Zydus Lifesciences, focuses on early-stage and growth-stage healthcare companies, providing financial and strategic support to drive meaningful advancements in medical science.
Illexcor Therapeutics is dedicated to developing innovative oral treatments for SCD, with ILX002 leading its pipeline as a potential breakthrough therapy for this genetic disorder.
The investment by Zydus Lifesciences’ Zynext Ventures in Illexcor Therapeutics marks a significant step towards advancing innovative treatments for sickle cell disease. With ILX002 moving towards clinical trials, this collaboration has the potential to address a critical unmet medical need globally. As research progresses, it could pave the way for a transformative oral therapy that improves patient outcomes.
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Published on: Mar 13, 2025, 1:45 PM IST
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